Welcome to the Molecular Phenotyping and Imaging Core Facility (MPIC)
The Molecular Phenotyping and Imaging Core Facility (MPIC) is overseen by the Firestone Institute for Respiratory Health (FIRH). MPIC performs molecular phenotyping on experimental and clinical research.
Using paraffin-embedded (FFPE) tissues, we can create tissue microarrays (TMAs), perform various immunostaining techniques (IHC, ISH, FISH, CTC and Multiplexing) through our sister-Core Facility at McMaster, high-throughput slide scanning and image digitization as well as quantitative tissue analyses for digital pathology.
Select any of the tiles below to learn more about how you can collaborate with MPIC!
Information Box Group
MPIC Overview
TMA Overview
HALO Overview
Information Box Group
Facility Learn More
Request our collaboration with creating Tissue Microarrays (TMA), Histology (STAIN), performing Slide Digitization (SCAN) and Tissue Analysis (HALO).
Personnel Learn More
Our co-directors Nathan Hambly and Jeremy Hirota lead our team of core personnel.
Contact Us Learn More
If you’d like to collaborate with us, please get in touch with one of our trained personnel!
Find Us Learn More
The MPIC facility is located within the Firestone Institute for Respiratory Health (FIRH) in Room L314 of the Luke Wing at St. Joseph’s Hamilton Healthcare.
MPIC-Collaborated Publications
BMC ➚
Potentiation of long-acting B2-agonist and glucocorticoid responses in human airway epithelial cells by modulation of intracellular cAMP
MPIC-Collaborated Publications
MDPI ➚
A Robust Protocol for Decellularized Human Lung Bioink Generation Amenable to 2D and 3D Lung Cell Culture
MPIC-Collaborated Publications
ERS Publications ➚
Expression of endocannabinoid system components in human airway epithelial cells: impact of sex and chronic respiratory disease status
MPIC-Collaborated Publications
ERS Publications ➚
Suboptimal treatment response to anti-IL-5 monoclonal antibodies in severe eosinophilic asthmatics with airway autoimmune phenomena
MPIC-Collaborated Publications
Frontiers ➚
ABCF1 Regulates dsDNA-induced Immune Responses in Human Airway Epithelial Cells
MPIC-Collaborated Publications
ERS Journals ➚
Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue
MPIC-Collaborated Publications
Science Direct ➚
Inhalation: A means to explore and optimize nintedanib's pharmacokinetic/ pharmacodynamic relationship
MPIC-Collaborated Publications